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Joshua M. Lang, MD, of the University of Wisconsin Carbone Cancer Center, discusses genomic alterations in DNA damage–repair pathways––more common in patients with prostate cancer than previously recognized–– and clinical trials with PARP inhibitors.

Joshua M. Lang, MD, on Prostate Cancer: Best of the Journals

⏲ 93 sec ✓ 21-Feb-2017

Touch Medical Media Services

PARP inhibitors in ovarian cancer: Clinical updates from SGO 2023

⏲ 59 minutes 14 seconds 👁 1,000

James L. Gulley, MD, PhD, of the National Cancer Institute, discusses combined treatment approaches showing early evidence of clinical activity: agents such as vaccines or PARP inhibitors that can initiate an immune response, paired with agents such as checkpoint inhibitors that can facilitate the activity of tumor-directed immune cells.

James L. Gulley, MD, PhD, on Prostate Cancer: Expanding Immunotherapy Options

⏲ 2 min 33 sec ✓ 28-Jan-2018

Stenoparib Publication in MBio JournalnnStenoparib, an inhibitor of cellular poly (ADP-ribose) polymerase (PARP), blocks replication of the SARS-CoV-2 and HCoV-NL63 human coronaviruses in vitro.nnMore info: https://joinpmi.com/ctsc-stenoparib-and-covid-19

CTSC | Stenoparib and COVID-19

⏲ 1 min 76 sec ✓ 16-Feb-2021

In this GU CONNECT programme from Dr Andrew Armstrong, you'll follow a patient through their prostate cancer journey and explore the clinical implementation of genetic testing and PARP inhibitors in combination with novel hormonal agents (NHAs). It follows Dr Neal Shore's animated video exploring PARPis as monotherapy.nnWatch the animated video and download the accompanying slides for an update on:nn- Efficacy and safety profiles of PARP inhibitors for prostate cancern- The role of genetic testi

PARP inhibitors in combination with NHAs

⏲ 3 min 59 sec ✓ 12-Jul-2023

Prostate cancer expert Dr. Channing Paller reviews key variables that impact prostate cancer treatment decisions and explains immunotherapy, PARP inhibitors, and personalized medicine.nnDr. Channing Paller is Director of Prostate Cancer Clinical Research at Johns Hopkins Medicine. Learn more about Dr. Paller here: https://www.hopkinsmedicine.org/profiles/details/channing-paller

What Key Factors Impact Prostate Cancer Treatment Decisions?

⏲ 4 min 15 sec ✓ 27-Jul-2023

2021-07-09 PARP-i for non-HRD population - Dr. Ryan Spencer.mp4 from parp

2021-07-09 PARP-i for non-HRD population - Dr. Ryan Spencer.mp4

⏲ 19 min 18 sec ✓ 14-Jul-2021

How do genetic test results impact prostate cancer treatment options? Dr. Nima Sharifi explains BRCA mutations, germline genes, and somatic mutations—and discusses when treatment with PARP inhibitors may be appropriate. Dr. Nima Sharifi is Director of the Genitourinary (GU) Malignancies Research Center at the Cleveland Clinic. Learn more here: https://www.lerner.ccf.org/cancerbio/sharifi/

Prostate Cancer Treatment Decisions: How Do Genetic Test Results Impact Your Options?

⏲ 2 min 54 sec ✓ 10-Dec-2020

What metastatic breast cancer (MBC) treatment options are available? Dr. Jane Lowe Meisel provides an overview of MBC treatment approaches, including CDK4-6 inhibitors, tyrosine kinase inhibitors, PARP inhibitors, and immunotherapy.nnJane Lowe Meisel, MD is an Associate Professor of Hematology and Medical Oncology at Winship Cancer Institute at Emory University. Learn more about Dr. Meisel here: https://winshipcancer.emory.edu/bios/faculty/meisel-jane-l.html

An Overview of Metastatic Breast Cancer Treatment Options

⏲ 2 min 86 sec ✓ 01-Sep-2021

A short 2D animation describing how a molecule, PARP-1, binds to DNA during the DNA repair process.

Negative Charge and Poly-ADP-Ribosylation: A Scientific Animation

⏲ 1 min 12 sec ✓ 07-Apr-2014

Muesli maketh the man.

⏲ 5 sec ✓ 04-Sep-2005

CreditsnCLIENT: PARPnAGENCY: Scholz & FriendsnPRODUCTION: Dorota SieradzkanANIMATION DIRECTOR: Michal Socha, BrosFXnCREATION: Agnieszka Niska- Wojcik, BrosFXnREALIZATION: BrosFX: Directing, Concept Design, Animation, Postproduction

⏲ 30 sec ✓ 14-Nov-2012

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