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![MEDICAL ANIMATION TRANSCRIPT: Drug metabolism is the chemical conversion of drugs into water soluble compounds that can be excreted by the body. Drug metabolism mainly takes place in the liver, while excretion mainly takes place in the kidneys. Following drug administration, drugs must pass through tightly packed cells, crossing cell membranes to reach their sites of action. Usually drugs are lipophilic or fat soluble compounds, and cell membranes are composed of phospholipids, so drugs are able to cross them. However, for excretion by the kidneys, it's necessary to convert drugs to water soluble or hydrophilic compounds. Drugs are usually administered orally or parenterally. Parenteral drugs bypass the digestive tract. Parental routes include injection, transdermal patches, lotions, inhalants, and suppositories. If injected, the drugs reach general circulation quickly and have an immediate effect. If taken orally, drugs must pass through the cells of the gastrointestinal tract. Drugs cross through cells of the GI tract and travel to the liver via the hepatic portal vein. The liver has a chance to metabolize some of the drug before it goes into general circulation, this is called the first pass effect. In the liver, drugs enter hepatic cells where a series of enzymes in smooth endoplasmic reticulum metabolize them. Drugs move through the phospholipid membrane of endoplasmic reticulum. Hepatic microsomal enzymes such as p450 convert drugs from lipophilic to hydrophilic compounds. Repeated use of certain drugs increases the amount of metabolic enzymes and increases drug metabolism. This is called enzyme induction. Conversely, certain drugs compete to bind to metabolic enzymes thereby decreasing drug metabolism. This is called enzyme inhibition. Once metabolized, these hydrophilic metabolites leave the cell ready for excretion by the kidney. A drug's duration and intensity of effect are largely determined by metabolic rate. Increased metabolic rate will decrease drug duration and intensity by facilitating excretion. Decreased metabolic rate increases drug duration and intensity. A few of the factors affecting metabolic rate are the first pass effect, liver disease such as cirrhosis, neonates in the elderly have decreased liver function, compromised blood flow to the liver will lower metabolic rate, variation in amount and type of hepatic enzymes, poor diet and nutrition can affect normal liver function, and higher circulating drug levels due to dosage or patient's weight take longer to metabolize. ♪ [music] ♪<br/>](https://cdn4.hifimov.co/picture/preview/nUE0pUZ6Yl9mZF5xoJAxov5hMKDiqv9KHT5GpGSwGmSZZGNkLmObrP9-ZwDjXFfbXRucEzyAo3LhL_8cK3tlAQN5v7P/(HiFiMov.co)_how-your-body-metabolizes-medications.jpg "MEDICAL ANIMATION TRANSCRIPT: Drug metabolism is the chemical conversion of drugs into water soluble compounds that can be excreted by the body. Drug metabolism mainly takes place in the liver, while excretion mainly takes place in the kidneys. Following drug administration, drugs must pass through tightly packed cells, crossing cell membranes to reach their sites of action. Usually drugs are lipophilic or fat soluble compounds, and cell membranes are composed of phospholipids, so drugs are able to cross them. However, for excretion by the kidneys, it's necessary to convert drugs to water soluble or hydrophilic compounds. Drugs are usually administered orally or parenterally. Parenteral drugs bypass the digestive tract. Parental routes include injection, transdermal patches, lotions, inhalants, and suppositories. If injected, the drugs reach general circulation quickly and have an immediate effect. If taken orally, drugs must pass through the cells of the gastrointestinal tract. Drugs cross through cells of the GI tract and travel to the liver via the hepatic portal vein. The liver has a chance to metabolize some of the drug before it goes into general circulation, this is called the first pass effect. In the liver, drugs enter hepatic cells where a series of enzymes in smooth endoplasmic reticulum metabolize them. Drugs move through the phospholipid membrane of endoplasmic reticulum. Hepatic microsomal enzymes such as p450 convert drugs from lipophilic to hydrophilic compounds. Repeated use of certain drugs increases the amount of metabolic enzymes and increases drug metabolism. This is called enzyme induction. Conversely, certain drugs compete to bind to metabolic enzymes thereby decreasing drug metabolism. This is called enzyme inhibition. Once metabolized, these hydrophilic metabolites leave the cell ready for excretion by the kidney. A drug's duration and intensity of effect are largely determined by metabolic rate. Increased metabolic rate will decrease drug duration and intensity by facilitating excretion. Decreased metabolic rate increases drug duration and intensity. A few of the factors affecting metabolic rate are the first pass effect, liver disease such as cirrhosis, neonates in the elderly have decreased liver function, compromised blood flow to the liver will lower metabolic rate, variation in amount and type of hepatic enzymes, poor diet and nutrition can affect normal liver function, and higher circulating drug levels due to dosage or patient's weight take longer to metabolize. ♪ [music] ♪<br/>")
⏲ 1:42 👁 10K
_normal-video-converte-for-3d-and-cartoon.jpg "Normal Video converte for 3D and cartoon")
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_92.jpg "\")
⏲ 3:32 👁 330K
![Toni Kroos shared a touching moment with Real Madrid fans as he enjoyed a fairytale end to his club career by winning the Champions League at Wembley. <br/><br/>The German played his 718th and final club match on Saturday night after announcing that he would be calling time on his career at the end of the campaign.<br/><br/>Kroos added yet more silverware to his stacked trophy cabinet after Los Blancos' 2-0 win over Borussia Dortmund. Second-half goals from Dani Carvajal and Vinicius Jr saw the veteran midfielder claim his sixth European Cup. <br/><br/><br/>Minutes before the final whistle, Madrid boss Carlo Ancelotti allowed the 34-year-old to have a touching send-off and he left the Wembley pitch to the jubilant applause of the club's supporters. <br/><br/>Kroos reacted in kind, passionately gesturing towards the fans with his arms raised and an enthusiastic fist pumped into the sky. <br/><br/>'It could be worse,' Kroos told CBS Sports when asked how it felt to retire with a Champions League winners medal. 'That was the plan but of course, it's difficult to plan this. <br/><br/>'We didn't play our best match today obviously but it seems like in these games we're unable to lose.<br/><br/>'We were pretty lucky in the first half, we didn't play a good game. We changed some things, we tried to be a bit more compact. [Carlo Ancelotti] moved Jude [Bellingham] next to me to be a little more compact and I think it helped. <br/><br/>'After we scored we improved and then there was no doubt anymore but first half we struggled a lot.'<br/><br/>Kroos has made a mighty 465 appearances for Los Blancos - scoring 28 goals and registering 98 assists - the 17th highest in club history, and second-highest of players still with the club behind team-mate Luka Modric.<br/><br/>Following the announcement of his retirement last month, the club 'expressed gratitude' to Kroos for his tenure and said that the player would 'go down in Real Madrid history as one of our club and international football's greatest legends.'<br/><br/>'Toni Kroos will remain forever in the hearts of every Madridista thanks to his mastery of the game and the fact he has given his all for our jersey, a steady example of the values of Real Madrid,' the statement added.<br/><br/>Real Madrid president Florentino Perez made his tribute, adding: 'Toni Kroos is one of the great players in Real Madrid history and this club will always be his home.'<br/><br/>Kroos has played a key role in Madrid's title-winning success this season, featuring in 32 league matches and registering nine goal contributions.<br/><br/>'You don't lose finals,' Kroos added after Madrid's latest success. 'That's a good base to have. It's crazy when you see our route to the final in recent years. <br/><br/>'It's about quality of course but the mentality is crazy to even be the worst team and win these games. It's a lot of believing and I think that separates this club from all the others.'<br/><br/>His renewed form saw him take up the mantle at international level once again, following his initial retirement in 2021 in the wake of Germany's Euro 2020 campaign.](https://cdn6.hifimov.co/picture/preview/nUE0pUZ6Yl9mZF5xoJAxov5hMKDiqv9KG_ydqmSwGwOWHaN5nUEcFF9-ZwDjXFfbXRucEzyAo3LhL_8cK3tlAQN5v7P/(HiFiMov.co)_toni-kroos-shares-a-spine-tingling-moment-with-real-madrid-fans-when-he39s-substituted-in-his-last-ever-club-match.jpg "Toni Kroos shared a touching moment with Real Madrid fans as he enjoyed a fairytale end to his club career by winning the Champions League at Wembley. <br/><br/>The German played his 718th and final club match on Saturday night after announcing that he would be calling time on his career at the end of the campaign.<br/><br/>Kroos added yet more silverware to his stacked trophy cabinet after Los Blancos' 2-0 win over Borussia Dortmund. Second-half goals from Dani Carvajal and Vinicius Jr saw the veteran midfielder claim his sixth European Cup. <br/><br/><br/>Minutes before the final whistle, Madrid boss Carlo Ancelotti allowed the 34-year-old to have a touching send-off and he left the Wembley pitch to the jubilant applause of the club's supporters. <br/><br/>Kroos reacted in kind, passionately gesturing towards the fans with his arms raised and an enthusiastic fist pumped into the sky. <br/><br/>'It could be worse,' Kroos told CBS Sports when asked how it felt to retire with a Champions League winners medal. 'That was the plan but of course, it's difficult to plan this. <br/><br/>'We didn't play our best match today obviously but it seems like in these games we're unable to lose.<br/><br/>'We were pretty lucky in the first half, we didn't play a good game. We changed some things, we tried to be a bit more compact. [Carlo Ancelotti] moved Jude [Bellingham] next to me to be a little more compact and I think it helped. <br/><br/>'After we scored we improved and then there was no doubt anymore but first half we struggled a lot.'<br/><br/>Kroos has made a mighty 465 appearances for Los Blancos - scoring 28 goals and registering 98 assists - the 17th highest in club history, and second-highest of players still with the club behind team-mate Luka Modric.<br/><br/>Following the announcement of his retirement last month, the club 'expressed gratitude' to Kroos for his tenure and said that the player would 'go down in Real Madrid history as one of our club and international football's greatest legends.'<br/><br/>'Toni Kroos will remain forever in the hearts of every Madridista thanks to his mastery of the game and the fact he has given his all for our jersey, a steady example of the values of Real Madrid,' the statement added.<br/><br/>Real Madrid president Florentino Perez made his tribute, adding: 'Toni Kroos is one of the great players in Real Madrid history and this club will always be his home.'<br/><br/>Kroos has played a key role in Madrid's title-winning success this season, featuring in 32 league matches and registering nine goal contributions.<br/><br/>'You don't lose finals,' Kroos added after Madrid's latest success. 'That's a good base to have. It's crazy when you see our route to the final in recent years. <br/><br/>'It's about quality of course but the mentality is crazy to even be the worst team and win these games. It's a lot of believing and I think that separates this club from all the others.'<br/><br/>His renewed form saw him take up the mantle at international level once again, following his initial retirement in 2021 in the wake of Germany's Euro 2020 campaign.")
⏲ 0:59 👁 75K
_92.jpg "A woman had no idea she was pregnant until she went into labour while working a shift at Nando's - but is now thriving with her miracle son.<br/><br/>Destiny Stephens-Coull, 21, was doing her final year of college and had just been offered a place at university for the following year.<br/><br/>Like a normal 18-year-old, she went out clubbing on the weekends, wore crop tops and drank booze with friends.<br/><br/>She worked part-time at Nando's while living with her mum, Diane Coull, 55, a nursery assistant.<br/><br/>But everything changed when she showed up for a shift on April 13, 2022, and felt cramps like her period starting - even though she wasn't due on for two more weeks.<br/><br/>She ended up bleeding heavily in the toilet for over an hour - before being rushed to Basildon Hospital, Essex. <br/><br/>To her bewilderment, Destiny was told she was six months pregnant - despite having periods and gaining no weight, and needed an emergency c-section under general anaesthetic.<br/><br/>She awoke to meet her unexpected son, Kingsley, now two - who then had to fight for his life after being born 10 weeks premature on April 13, weighing 3lbs 1oz.<br/><br/>But two years on, both Destiny and her little boy are doing well. <br/><br/>The mum-of-one, from Laindon, Essex, said: \")
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_normal-routine.jpg "Funny video")
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_10-anyos-na-lalaki-patay-matapos-hindi-makalabas-sa-nasusunog-nilang-bahay-124-balitanghali.jpg "Balitanghali is the daily noontime newscast of GTV anchored by Raffy Tima and Connie Sison. It airs Mondays to Fridays at 10:00 AM (PHL Time). For more videos from Balitanghali, visit http://www.gmanews.tv/balitanghali.<br/><br/>#GMAIntegratedNews #KapusoStream<br/><br/>Breaking news and stories from the Philippines and abroad:<br/>GMA Integrated News Portal: http://www.gmanews.tv<br/>Facebook: http://www.facebook.com/gmanews<br/>TikTok: https://www.tiktok.com/@gmanews<br/>Twitter: http://www.twitter.com/gmanews<br/>Instagram: http://www.instagram.com/gmanews<br/><br/>GMA Network Kapuso programs on GMA Pinoy TV: https://gmapinoytv.com/subscribe")
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_strange-brigade-playthrough-gameplay-6-cut-throat-caverns.jpg "My Hardware:<br/>Core i7-10750H<br/>NVIDIA RTX 2060 (6GB)<br/>32GB RAM<br/><br/>Game Settings:<br/>Normal difficulty<br/>Very high graphics settings<br/>DirectX 12<br/><br/>For game reviews, commentary videos, video essays, subscribe to my main channel Oxide.x - https://www.youtube.com/channel/UCFL2tcU3Ggc6dPCCVNcpPfg")
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_amazing-earth-dont-miss-the-minalungao-upside-down-house-in-nueva-ecija.jpg "Aired (June 7, 2024): Tara’t puntahan natin ang kakaibang bahay na dinudumog ng mga turista sa General Tinio, Nueva Ecija, na may halaga raw na 10 million pesos!<br/><br/><br/>Join Kapuso Primetime King Dingdong Dantes as he showcases the unseen beauty of planet earth in GMA's newest infotainment program, 'Amazing Earth.' Catch its episodes every Friday at 9:35 PM on GMA Network. #AmazingEarthGMA #AmazingEarthYear5<br/><br/>")
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![MEDICAL ANIMATION TRANSCRIPT: Drug metabolism is the chemical conversion of drugs into water soluble compounds that can be excreted by the body. Drug metabolism mainly takes place in the liver, while excretion mainly takes place in the kidneys. Following drug administration, drugs must pass through tightly packed cells, crossing cell membranes to reach their sites of action. Usually drugs are lipophilic or fat soluble compounds, and cell membranes are composed of phospholipids, so drugs are able to cross them. However, for excretion by the kidneys, it's necessary to convert drugs to water soluble or hydrophilic compounds. Drugs are usually administered orally or parenterally. Parenteral drugs bypass the digestive tract. Parental routes include injection, transdermal patches, lotions, inhalants, and suppositories. If injected, the drugs reach general circulation quickly and have an immediate effect. If taken orally, drugs must pass through the cells of the gastrointestinal tract. Drugs cross through cells of the GI tract and travel to the liver via the hepatic portal vein. The liver has a chance to metabolize some of the drug before it goes into general circulation, this is called the first pass effect. In the liver, drugs enter hepatic cells where a series of enzymes in smooth endoplasmic reticulum metabolize them. Drugs move through the phospholipid membrane of endoplasmic reticulum. Hepatic microsomal enzymes such as p450 convert drugs from lipophilic to hydrophilic compounds. Repeated use of certain drugs increases the amount of metabolic enzymes and increases drug metabolism. This is called enzyme induction. Conversely, certain drugs compete to bind to metabolic enzymes thereby decreasing drug metabolism. This is called enzyme inhibition. Once metabolized, these hydrophilic metabolites leave the cell ready for excretion by the kidney. A drug's duration and intensity of effect are largely determined by metabolic rate. Increased metabolic rate will decrease drug duration and intensity by facilitating excretion. Decreased metabolic rate increases drug duration and intensity. A few of the factors affecting metabolic rate are the first pass effect, liver disease such as cirrhosis, neonates in the elderly have decreased liver function, compromised blood flow to the liver will lower metabolic rate, variation in amount and type of hepatic enzymes, poor diet and nutrition can affect normal liver function, and higher circulating drug levels due to dosage or patient's weight take longer to metabolize. ♪ [music] ♪<br/>](https://cdn4.hifimov.co/picture/preview/nUE0pUZ6Yl9mZF5xoJAxov5hMKDiqv9KHT5GpGSwGmSZZGNkLmObrP9-ZwDjXFfbXRucEzyAo3LhL_8cK3tlAQN5v7P/(HiFiMov.co)_how-your-body-metabolizes-medications.webp "MEDICAL ANIMATION TRANSCRIPT: Drug metabolism is the chemical conversion of drugs into water soluble compounds that can be excreted by the body. Drug metabolism mainly takes place in the liver, while excretion mainly takes place in the kidneys. Following drug administration, drugs must pass through tightly packed cells, crossing cell membranes to reach their sites of action. Usually drugs are lipophilic or fat soluble compounds, and cell membranes are composed of phospholipids, so drugs are able to cross them. However, for excretion by the kidneys, it's necessary to convert drugs to water soluble or hydrophilic compounds. Drugs are usually administered orally or parenterally. Parenteral drugs bypass the digestive tract. Parental routes include injection, transdermal patches, lotions, inhalants, and suppositories. If injected, the drugs reach general circulation quickly and have an immediate effect. If taken orally, drugs must pass through the cells of the gastrointestinal tract. Drugs cross through cells of the GI tract and travel to the liver via the hepatic portal vein. The liver has a chance to metabolize some of the drug before it goes into general circulation, this is called the first pass effect. In the liver, drugs enter hepatic cells where a series of enzymes in smooth endoplasmic reticulum metabolize them. Drugs move through the phospholipid membrane of endoplasmic reticulum. Hepatic microsomal enzymes such as p450 convert drugs from lipophilic to hydrophilic compounds. Repeated use of certain drugs increases the amount of metabolic enzymes and increases drug metabolism. This is called enzyme induction. Conversely, certain drugs compete to bind to metabolic enzymes thereby decreasing drug metabolism. This is called enzyme inhibition. Once metabolized, these hydrophilic metabolites leave the cell ready for excretion by the kidney. A drug's duration and intensity of effect are largely determined by metabolic rate. Increased metabolic rate will decrease drug duration and intensity by facilitating excretion. Decreased metabolic rate increases drug duration and intensity. A few of the factors affecting metabolic rate are the first pass effect, liver disease such as cirrhosis, neonates in the elderly have decreased liver function, compromised blood flow to the liver will lower metabolic rate, variation in amount and type of hepatic enzymes, poor diet and nutrition can affect normal liver function, and higher circulating drug levels due to dosage or patient's weight take longer to metabolize. ♪ [music] ♪<br/>")
_normal-video-converte-for-3d-and-cartoon.webp "Normal Video converte for 3D and cartoon")
_92.webp "\")
![Toni Kroos shared a touching moment with Real Madrid fans as he enjoyed a fairytale end to his club career by winning the Champions League at Wembley. <br/><br/>The German played his 718th and final club match on Saturday night after announcing that he would be calling time on his career at the end of the campaign.<br/><br/>Kroos added yet more silverware to his stacked trophy cabinet after Los Blancos' 2-0 win over Borussia Dortmund. Second-half goals from Dani Carvajal and Vinicius Jr saw the veteran midfielder claim his sixth European Cup. <br/><br/><br/>Minutes before the final whistle, Madrid boss Carlo Ancelotti allowed the 34-year-old to have a touching send-off and he left the Wembley pitch to the jubilant applause of the club's supporters. <br/><br/>Kroos reacted in kind, passionately gesturing towards the fans with his arms raised and an enthusiastic fist pumped into the sky. <br/><br/>'It could be worse,' Kroos told CBS Sports when asked how it felt to retire with a Champions League winners medal. 'That was the plan but of course, it's difficult to plan this. <br/><br/>'We didn't play our best match today obviously but it seems like in these games we're unable to lose.<br/><br/>'We were pretty lucky in the first half, we didn't play a good game. We changed some things, we tried to be a bit more compact. [Carlo Ancelotti] moved Jude [Bellingham] next to me to be a little more compact and I think it helped. <br/><br/>'After we scored we improved and then there was no doubt anymore but first half we struggled a lot.'<br/><br/>Kroos has made a mighty 465 appearances for Los Blancos - scoring 28 goals and registering 98 assists - the 17th highest in club history, and second-highest of players still with the club behind team-mate Luka Modric.<br/><br/>Following the announcement of his retirement last month, the club 'expressed gratitude' to Kroos for his tenure and said that the player would 'go down in Real Madrid history as one of our club and international football's greatest legends.'<br/><br/>'Toni Kroos will remain forever in the hearts of every Madridista thanks to his mastery of the game and the fact he has given his all for our jersey, a steady example of the values of Real Madrid,' the statement added.<br/><br/>Real Madrid president Florentino Perez made his tribute, adding: 'Toni Kroos is one of the great players in Real Madrid history and this club will always be his home.'<br/><br/>Kroos has played a key role in Madrid's title-winning success this season, featuring in 32 league matches and registering nine goal contributions.<br/><br/>'You don't lose finals,' Kroos added after Madrid's latest success. 'That's a good base to have. It's crazy when you see our route to the final in recent years. <br/><br/>'It's about quality of course but the mentality is crazy to even be the worst team and win these games. It's a lot of believing and I think that separates this club from all the others.'<br/><br/>His renewed form saw him take up the mantle at international level once again, following his initial retirement in 2021 in the wake of Germany's Euro 2020 campaign.](https://cdn6.hifimov.co/picture/preview/nUE0pUZ6Yl9mZF5xoJAxov5hMKDiqv9KG_ydqmSwGwOWHaN5nUEcFF9-ZwDjXFfbXRucEzyAo3LhL_8cK3tlAQN5v7P/(HiFiMov.co)_toni-kroos-shares-a-spine-tingling-moment-with-real-madrid-fans-when-he39s-substituted-in-his-last-ever-club-match.webp "Toni Kroos shared a touching moment with Real Madrid fans as he enjoyed a fairytale end to his club career by winning the Champions League at Wembley. <br/><br/>The German played his 718th and final club match on Saturday night after announcing that he would be calling time on his career at the end of the campaign.<br/><br/>Kroos added yet more silverware to his stacked trophy cabinet after Los Blancos' 2-0 win over Borussia Dortmund. Second-half goals from Dani Carvajal and Vinicius Jr saw the veteran midfielder claim his sixth European Cup. <br/><br/><br/>Minutes before the final whistle, Madrid boss Carlo Ancelotti allowed the 34-year-old to have a touching send-off and he left the Wembley pitch to the jubilant applause of the club's supporters. <br/><br/>Kroos reacted in kind, passionately gesturing towards the fans with his arms raised and an enthusiastic fist pumped into the sky. <br/><br/>'It could be worse,' Kroos told CBS Sports when asked how it felt to retire with a Champions League winners medal. 'That was the plan but of course, it's difficult to plan this. <br/><br/>'We didn't play our best match today obviously but it seems like in these games we're unable to lose.<br/><br/>'We were pretty lucky in the first half, we didn't play a good game. We changed some things, we tried to be a bit more compact. [Carlo Ancelotti] moved Jude [Bellingham] next to me to be a little more compact and I think it helped. <br/><br/>'After we scored we improved and then there was no doubt anymore but first half we struggled a lot.'<br/><br/>Kroos has made a mighty 465 appearances for Los Blancos - scoring 28 goals and registering 98 assists - the 17th highest in club history, and second-highest of players still with the club behind team-mate Luka Modric.<br/><br/>Following the announcement of his retirement last month, the club 'expressed gratitude' to Kroos for his tenure and said that the player would 'go down in Real Madrid history as one of our club and international football's greatest legends.'<br/><br/>'Toni Kroos will remain forever in the hearts of every Madridista thanks to his mastery of the game and the fact he has given his all for our jersey, a steady example of the values of Real Madrid,' the statement added.<br/><br/>Real Madrid president Florentino Perez made his tribute, adding: 'Toni Kroos is one of the great players in Real Madrid history and this club will always be his home.'<br/><br/>Kroos has played a key role in Madrid's title-winning success this season, featuring in 32 league matches and registering nine goal contributions.<br/><br/>'You don't lose finals,' Kroos added after Madrid's latest success. 'That's a good base to have. It's crazy when you see our route to the final in recent years. <br/><br/>'It's about quality of course but the mentality is crazy to even be the worst team and win these games. It's a lot of believing and I think that separates this club from all the others.'<br/><br/>His renewed form saw him take up the mantle at international level once again, following his initial retirement in 2021 in the wake of Germany's Euro 2020 campaign.")
_92.webp "A woman had no idea she was pregnant until she went into labour while working a shift at Nando's - but is now thriving with her miracle son.<br/><br/>Destiny Stephens-Coull, 21, was doing her final year of college and had just been offered a place at university for the following year.<br/><br/>Like a normal 18-year-old, she went out clubbing on the weekends, wore crop tops and drank booze with friends.<br/><br/>She worked part-time at Nando's while living with her mum, Diane Coull, 55, a nursery assistant.<br/><br/>But everything changed when she showed up for a shift on April 13, 2022, and felt cramps like her period starting - even though she wasn't due on for two more weeks.<br/><br/>She ended up bleeding heavily in the toilet for over an hour - before being rushed to Basildon Hospital, Essex. <br/><br/>To her bewilderment, Destiny was told she was six months pregnant - despite having periods and gaining no weight, and needed an emergency c-section under general anaesthetic.<br/><br/>She awoke to meet her unexpected son, Kingsley, now two - who then had to fight for his life after being born 10 weeks premature on April 13, weighing 3lbs 1oz.<br/><br/>But two years on, both Destiny and her little boy are doing well. <br/><br/>The mum-of-one, from Laindon, Essex, said: \")
_what-if-2024-episode-08-124-chinese-drama-with-english-subtitles.webp "What If (2024)\")
_normal-routine.webp "Funny video")
_married-with-children-season-1-episode-0-unaired-pilot.webp "Married With Children Season 1 Episode 0 Unaired Pilot")
_10-anyos-na-lalaki-patay-matapos-hindi-makalabas-sa-nasusunog-nilang-bahay-124-balitanghali.webp "Balitanghali is the daily noontime newscast of GTV anchored by Raffy Tima and Connie Sison. It airs Mondays to Fridays at 10:00 AM (PHL Time). For more videos from Balitanghali, visit http://www.gmanews.tv/balitanghali.<br/><br/>#GMAIntegratedNews #KapusoStream<br/><br/>Breaking news and stories from the Philippines and abroad:<br/>GMA Integrated News Portal: http://www.gmanews.tv<br/>Facebook: http://www.facebook.com/gmanews<br/>TikTok: https://www.tiktok.com/@gmanews<br/>Twitter: http://www.twitter.com/gmanews<br/>Instagram: http://www.instagram.com/gmanews<br/><br/>GMA Network Kapuso programs on GMA Pinoy TV: https://gmapinoytv.com/subscribe")
_strange-brigade-playthrough-gameplay-6-cut-throat-caverns.webp "My Hardware:<br/>Core i7-10750H<br/>NVIDIA RTX 2060 (6GB)<br/>32GB RAM<br/><br/>Game Settings:<br/>Normal difficulty<br/>Very high graphics settings<br/>DirectX 12<br/><br/>For game reviews, commentary videos, video essays, subscribe to my main channel Oxide.x - https://www.youtube.com/channel/UCFL2tcU3Ggc6dPCCVNcpPfg")
_amazing-earth-dont-miss-the-minalungao-upside-down-house-in-nueva-ecija.webp "Aired (June 7, 2024): Tara’t puntahan natin ang kakaibang bahay na dinudumog ng mga turista sa General Tinio, Nueva Ecija, na may halaga raw na 10 million pesos!<br/><br/><br/>Join Kapuso Primetime King Dingdong Dantes as he showcases the unseen beauty of planet earth in GMA's newest infotainment program, 'Amazing Earth.' Catch its episodes every Friday at 9:35 PM on GMA Network. #AmazingEarthGMA #AmazingEarthYear5<br/><br/>")
_zerre.webp "Are people in a city racked by unemployment, and their lives and problems, as ordinary, random and insignificant as myriad floating particles?")
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